Chitosan Concentration in Aqueous Media via Electrical Conductivity
Article Sidebar
Main Article Content
Abstract
Abstract
Chitosan is the deacetylated polymer of chitin. Chitosan has many advantageous properties such as biodegradability, biocompatibility, nontoxicity, and hydrophilicity. It is also antioxidant, antimicrobial, renewable, and low-cost. The properties and potential uses of chitosan have been of great interest to researchers for many years. Chitosan has limited solubility in neutral and alkali solutions. Many methods to quantify the chitosan concentration have been proposed i.e. UV–vis spectrophotometry, fluorspectrophotometry, cathodic stripping voltammetry, High-performance Liquid Chromatography (HPLC), and resonance Rayleigh scattering method. This paper proposed a practical non-invasive method for determining chitosan content in low-pH aqueous media.
Downloads
Article Details
Copyright (c) 2016 Šárka E, et al.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Biswas UK, Bose A, Ghosh B, Sharma S. An insight into chemically modified chitosan and their biological, pharmaceutical, and medical applications: A review. Int J Biol Macromol. 2025;303:140612. Available from: https://doi.org/10.1016/j.ijbiomac.2025.140612
Zhou Y, Zhang Y, Nie Y, Sun D, Wu D, Ban L, et al. Recent advances and perspectives in functional chitosan-based composites for environmental remediation, energy, and biomedical applications. Prog Mater Sci. 2025;152:101460. Available from: https://doi.org/10.1016/j.pmatsci.2025.101460
López-Iglesias C, Barros J, Ardao I, Monteiro FJ, Alvarez-Lorenzo C, Gómez-Amoza JL, et al. Vancomycin-loaded chitosan aerogel particles for chronic wound applications. Carbohydr Polym. 2019;204:223–231. Available from: https://doi.org/10.1016/j.carbpol.2018.10.012
Li Z, Li B, Li X, Lin Z, Chen L, Chen H, et al. Ultrafast in-situ forming halloysite nanotube-doped chitosan/oxidized dextran hydrogels for hemostasis and wound repair. Carbohydr Polym. 2021;267:118155. Available from: https://doi.org/10.1016/j.carbpol.2021.118155
Bano I, Arshad M, Yasin T, Ghauri MA, Younus M. Chitosan: A potential biopolymer for wound management. Int J Biol Macromol. 2017;102:380–383.
Li Y, Li X, Zhu L, Liu T, Huang L. Chitosan-based biomaterials for bone tissue engineering. Int J Biol Macromol. 2025;304(Pt 2):140923. Available from: https://doi.org/10.1016/j.ijbiomac.2025.140923
Rinaudo M. Chitin and chitosan: Properties and applications. Prog Polym Sci. 2006;31(7):603–632. https://doi.org/10.1016/j.progpolymsci.2006.06.001
Badazhkova VD, Raik SV, Polyakov DS, Skorik YuA. Transfection efficiency of cationic chitosan derivatives bearing quaternized and pyridine moieties. In: Proceedings of the 15th International Conference on Polysaccharides-Glycoscience; 2019;14–17.
Khachatryan G, Khachatryan K, Krystyjan M, Pardus L, Bebak E, Grzyb J. Formation and properties of chitosan/nanosilver bionanocomposite. In: Proceedings of the 14th International Conference on Polysaccharides-Glycoscience; 2018;191–195. Available from: https://agris.fao.org/search/en/providers/125458/records/67bdafd5e27dfa12518a4a01
Román-Doval R, Torres-Arellanes SP, Tenorio-Barajas AY, Gómez-Sánchez A, Valencia-Lazcano AA. Chitosan: Properties and its application in agriculture in context of molecular weight. Polymers. 2023;15:2867. Available from: https://doi.org/10.3390/polym15132867
Edo GI, Ndudi W, Ali ABM, Yousif E, Zainulabdeen K, Akpoghelie PO, et al. Chitosan: An overview of its properties, solubility, functional technologies, food and health applications. Carbohydr Res. 2025;550:109409. Available from: https://doi.org/10.1016/j.carres.2025.109409
Bai Y, Chen C, Chen Z, Su Z. Spectrophotometric determination of chitosan based on ion association reaction with Reactive Red 4. Food Sci. 2010;31:229–232.
González-Davis O, Betanzo I, Vazquez-Duhalt R. An accurate spectrophotometric method for chitosan quantification. Biol Methods Protoc. 2023;8(1):bpad036. Available from: https://doi.org/10.1093/biomethods/bpad036
Lu G, Wang L, Wang R, Zeng X, Huang Y. Determination of chitosan by cathodic stripping voltammetry. Anal Sci. 2006;22(4):575–578. Available from: https://link.springer.com/article/10.2116/analsci.22.575
Miao Q, Cui Y, Zhang J, Mi Y, Tan W, Li Q, et al. Determination of chitosan content with ratio coefficient method and HPLC. Int J Biol Macromol. 2020;164:384–388. Available from: https://doi.org/10.1016/j.ijbiomac.2020.07.013
Song M, Wang Y, Xiao T, Cai Z, Zou W, He J, et al. A resonance Rayleigh scattering method for sensitive detection of chitosan based on supramolecular complex and mechanism study. Spectrochim Acta A Mol Biomol Spectrosc. 2022;270:120797. Available from: https://doi.org/10.1016/j.saa.2021.120797
Alsulami QA, Bawazir WA, Keshk SMAS. Proton conductivity amelioration of chitosan via novel Schiff base formation with oxidized polyvinyl alcohol for proton exchange membrane. Emerg Mater. 2025. Available from: https://doi.org/10.1007/s42247-025-01051-6
Taheri AA, Rahmaninia M, Khosravani A. Interaction of the electrical conductivity of recycled pulp colloidal suspension with chitosan and bentonite as a papermaking additive system. BioResources. 2022;17(1):1805–1817. Available from: https://doi.org/10.15376/biores.17.1.1805-1817
Zou W, Song M, He J, Qiu P, Sun Z, Su Z, Bai Y. A resonance Rayleigh scattering and fluorescence quenching dual-channel sensor for sensitive detection of chitosan based on Eosin Y. Anal Bioanal Chem. 2021;413(5):1429–1440. Available from: https://doi.org/10.1007/s00216-020-03107-4